HIGHLIGHTS
- who: Pere Millat-Martinez from the The full COMPILEhome protocol is available as an online supplementThe study was designed as a Bayesian-adaptive individual patient data meta-analysis of ongoing clinical trials. Prior to the start of pooling, the study teams agreed upon a minimal set of data required to analyze the primary and secondary endpoints was agreed upon by the study teams. Each trial provided updated data every , weeks. The pooled data were monitored by , unblinded statisticians and a data and safety monitoring board (DSMB) every , weeks using a pre-established stopping guideline for efficacy. At . . .
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