Prostaglandin e2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor*

HIGHLIGHTS

• who: F. Gregory Buchanan from the (UNIVERSITY) have published the research work: Prostaglandin E2 Regulates Cell Migration via the Intracellular Activation of the Epidermal Growth Factor Receptor*, in the Journal: (JOURNAL) of March/11,/2003
• what: The authors demonstrate that the PGE2-induced migration and invasion occurs via rapid transactivation and phosphorylation of the epidermal growth factor receptor (EGFR). The authors report that PGE2 induced the activation of Akt within minutes, and this activation occurred through the EGFR. The authors show that EGFR-specific amounts of Akt in each sample are determined by Western analysis . . .
  

   

  

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