HIGHLIGHTS
- who: Tianbai Zhong from the (UNIVERSITY) have published the research: PROTAC mediated FKBP12 degradation enhances Hepcidin expression via BMP signaling without immunosuppression activity, in the Journal: (JOURNAL) of 16/Nov/2021
- how: The above results indicated that sharply in contrast with Rapamycin RC32 does not inhibit mTOR. To further confirm that RC32 does not possess immunosuppression activity the authors utilized the in_vitro PBMC (peripheral blood mononuclear cells) stimulation assay to compare these three drugs.
SUMMARY
Next, the authors verified whether RC32 had similar immunosuppression activity as FK506 or Rapamycin. Rapamycin, a . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.