Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein

HIGHLIGHTS

• who: Henning Leske and colleagues from the Institute of Neuropathology, University Hospital of Zurich, University of Zurich, Schmelzbergstrasse, Zurich, Switzerland have published the research work: Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0170503]. February 16, 2017 of /1371/
• what: The authors investigate the phenotypes arising in transgenic mice that express a minimal modification of the residue in position 169, i.e., replacing tyrosine (Y) by phenylalanine (F). The authors focused on the β2-α2 . . .
  

   

  

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