Proteasomal degradation of trim5 a during retrovirus restriction

HIGHLIGHTS

• who: Restriction and collaborators from the Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America have published the Article: Proteasomal Degradation of TRIM5 a during Retrovirus Restriction, in the Journal: (JOURNAL) of May/23,/2008
• what: The authors show that TRIM5a is rapidly degraded upon encounter of a restriction-susceptible retroviral core. The authors show that cellular TRIM5a is rapidly degraded in cells exposed to a restriction-sensitive retrovirus but not in cells infected with an unrestricted virus. The authors show that inoculation of PLoS Pathogens | www.plospathogens . . .
  

   

  

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