HIGHLIGHTS
- who: Ban Sato and colleagues from the University of Tsukuba, Tennodai, Tsukuba, Japan have published the paper: Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis, in the Journal: Biomolecules 2023, 586 of /2023/
- what: The authors demonstrated that dKO mice exhibited complete male infertility due to malformation in the midpiece of the sperm, and_(2) the accumulation of LPIN1 in dKO sperm caused the deposition of LDs and enhanced the number of mitochondria. The authors propose that proteasomes with PA200 and ECPAS play a role in mitochondrial sheath formation in sperm by . . .
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