Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets

HIGHLIGHTS

• who: Christophe Broca et al. from the CNRS UMR, INSERM, and Montpellier , and , University, Institute of Functional Genomics, Montpellier, France, Laboratory for Diabetes Cell Therapy, Institute have published the Article: Proteasome Dysfunction Mediates High Glucose-Induced Apoptosis in Rodent Beta Cells and Human Islets, in the Journal: PLOS ONE | www.plosone.org of March/18,/2014
• what: The aim of the study was to determine whether proteasome dysfunction could be involved in beta cell apoptosis in glucotoxic conditions and to evaluate whether such a dysfunction might be pharmacologically corrected. The authors assess ex vivo the . . .
  

   

  

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