Protections of transcription factor bach2 and natural product myricetin against pathological cardiac hypertrophy and dysfunction

HIGHLIGHTS

  • who: August et al. from the Louisiana State University Agricultural Center, United States have published the research work: Protections of transcription factor BACH2 and natural product myricetin against pathological cardiac hypertrophy and dysfunction, in the Journal: (JOURNAL)
  • what: To elucidate the potential mechanism underlining the role of BACH2 in cardiac hypertrophy and failure, the study showed that BACH2 bound to the promotor region of Akap6 at the -600 to -587 site and repressed its expression.
  • how: Taken together these results showed that myricetin exerted a BACH2-dependent protective effect against cardiac hypertrophy and . . .

     

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