Protective effect of astragaloside iv on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/sirt1/ampk signaling pathway

HIGHLIGHTS

• who: Astragaloside IV et al. from the Qatar University, Qatar University of Jaén, Spain have published the Article: Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway, in the Journal: (JOURNAL)
• what: The studies showed that SRT1720 ameliorated relaxation to ACh in CIH-exposed mice . HCAECs were used in this study since coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium, and were commonly used in cell model of CIH (Dancu and Tarbell, 2007; Zychowski et_al, 2016).
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