Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence

HIGHLIGHTS

  • who: Fei Ye et al. from the Department of Surgery/Surgical Oncology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America have published the research work: Protective Properties of Radio-Chemoresistant Glioblastoma Stem Cell Clones Are Associated with Metabolic Adaptation to Reduced Glucose Dependence, in the Journal: PLOS ONE | www.plosone.org of November/18,/2013
  • what: The authors show that most clonogenic cells in GSC cultures are sensitive to radiation treatment (RT) with or without temozolomide (TMZ). The authors explored the potential mechanisms underlying treatment resistance . . .

     

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