Protein complexes are under evolutionary selection to assemble via ordered pathways

HIGHLIGHTS

  • who: Joseph A. Marsh from the Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge , SD, UK University of have published the research work: Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways, in the Journal: (JOURNAL) of April/11,/2013
  • what: The authors seek to address this by searching for evidence of evolutionary selection for ordered complex assembly. By mapping gene fusion events identified from fully sequenced genomes onto complex assembly pathways the authors demonstrate evolutionary selection for conservation of assembly order. Using structural and high-throughput interaction data the authors show that . . .

     

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