HIGHLIGHTS
SUMMARY
The complete process involves a set of several amino_acids, with specific roles (Burgner and Ray 1984; Clarke et_al 1986, 1988; Deng et_al 1994, 2011; McClendon et_al 2005). In struc tures typical of the R-active state, a mobile loop that car ries the substrate discriminating glutamine Q102 covers the catalytic_site, allowing its dehydration and the correct anchoring of PYR with the side chain of R171, which pro trudes within the catalytic_site. The authors used the recently published LDH/MalDH phylogeny (Brochier-Armanet and Madern 2021) to reveal candidate amino_acids that could be linked to . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.