Protein folding activity of ribosomal rna is a selective target of two unrelated antiprion drugs

HIGHLIGHTS

• who: Déborah Tribouillard-Tanvier et al. from the Laboratory, Roscoff, France, Institute of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden, Laboratoire de Chimie Organique, Université have published the research work: Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs, in the Journal: (JOURNAL) of May/14,/2008
• what: Methodology/Principal Findings: Here the authors report the identification of cellular targets of these drugs. Using affinity chromatography matrices for both drugs the authors demonstrate an RNA-dependent interaction of 6AP and GA with the ribosome. The authors show . . .
  

   

  

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