Protein glutathionylation and glutaredoxin: role in neurodegenerative diseases

HIGHLIGHTS

  • who: Haseena P. A. and colleagues from the Centre for Brain Research, Indian Institute of Science, Bangalore, India have published the research: Protein Glutathionylation and Glutaredoxin: Role in Neurodegenerative Diseases, in the Journal: Antioxidants 2022, 2334 of /2022/
  • what: __SECTION__ Conclusions.

SUMMARY

    Super oxide dismutase (SOD) catalyzes Glutathione (GSH), the tripeptide in the form of γ-glutamyl cysteinyl glyc major thiol antioxidant responsible for the maintenance of protein thiol status in During the detoxification of ROS, glutathione peroxidase (GPx) oxidizes GSH t Glutaredoxin has a dual role; in the glutathionylation of sulfe . . .

     

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