HIGHLIGHTS
- who: Abbreviations HDAC and colleagues from the DepartmentSapienza University of Rome, Rome, Italy have published the article: Protein kinase C is required for cardiomyocyte survival and cardiac remodeling, in the Journal: (JOURNAL)
- what: The authors show that the expression/activity of the y-isoform of PKCs ensures the correct structure and function of cardiac muscle, at least in part, by protecting cardiomyocytes from cell death. Even ablation of PKCe, which is considered the most important isozyme protecting the heart from ischemia and reperfusion injury, did not exert any basal cardiac phenotype, although the combination of . . .
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