Protein kinase c life cycle: explained through systems biology approach

HIGHLIGHTS

  • who: Naveed Aslam and colleagues from the BioSystOmics, Houston, TX, United States, Department of Physics, COMSATS University Islamabad, Lahore Campus, Lahore have published the research: Protein Kinase C Life Cycle: Explained Through Systems Biology Approach, in the Journal: (JOURNAL)
  • what: The authors propose a molecular model of the PKC life cycle based on a systems biology approach. Rationale for the model proposed in this study was derived from many of the following experimental observations: 1) Depleted PKC has been observed in cells lacking kinases, such as PDK1 (Dutil et_al, 1998; Balendran et_al, 2000). Interestingly, activation . . .

     

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