Protein kinase ck2 represents a new target to boost ibrutinib and venetoclax induced cytotoxicity in mantle cell lymphoma

HIGHLIGHTS

  • who: TYPE and colleagues from the University of Padua, Italy have published the paper: Protein Kinase CK2 represents a new target to boost Ibrutinib and Venetoclax induced cytotoxicity in mantle cell lymphoma, in the Journal: (JOURNAL)
  • what: To confirm the possible synergism between CK2 and Bcl-2 inhibitions, the authors evaluate cell growth and calculated the CI between Frontiers in Cell and Developmental Biology frontiersin.org 10.3389/fcell.2022.935023 downstream elements, such as in the NF-κB pathway, BTK or PLCγ2 (Hershkovitz-Rokah et_al, 2018). The authors have provided strong evidence that . . .

     

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