Protein kinase inhibitors as a new target for immune system modulation and brain cancer management

HIGHLIGHTS

  • who: Alessia Filippone and collaborators from the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D`Alcontres, , Messina, Italy have published the research work: Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management, in the Journal: (JOURNAL)
  • what: The study showed that inhibition of CSF-1R signaling using PLX3397 reduced the number of microglia/macrophages and significantly inhibited invasiveness. This study showed that in the mouse model of GBM, treatment with Sunitinib reduced the number of MDSCs which coincided with an increase in . . .

     

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