HIGHLIGHTS
- What: The aim of this review is therefore to summarize recent data regarding the protein quality control of NKCC2 and to discuss their potential implications in BS and blood pressure regulation. To identify the ER exit signals(s) of NKCC2, the authors focused on the region downstream from Y998X, the most distal natural mutation identified in the carboxy-terminal tail of NKCC2 , as the key sequence governing the export of NKCC2 from the ER.
- Who: Kamel Laghmani from the Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France have published the . . .
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