Protein structural transitions critically transform the network connectivity and viscoelasticity of rna-binding protein condensates but rna can prevent it

HIGHLIGHTS

• who: Andres R. Tejedor from the (UNIVERSITY) have published the Article: Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it, in the Journal: (JOURNAL) of 30/03/2022
• what: To bridge microscopic understanding between accumulation of inter-protein u03b2-sheets over time and the modulation of FUS and hnRNPA1 condensate viscoelasticity, the authors develop a multiscale simulation approach. The authors develop a multiscale computational approach, integrating atomistic simulations and residue-resolution coarsegrained models to shed light on the thermodynamic and kinetic factors that explain . . .
  

   

  

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