Protein tyrosine phosphatase shp2 controls interleukin-8 expression in breast cancer cells

HIGHLIGHTS

  • who: Romain J. Amante from the Department of Biomedicine, University of Basel, University Hospital Basel, Basel, Switzerland have published the research work: Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells, in the Journal: (JOURNAL)
  • what: The authors investigated cytokines affected by SHP2 that could be relevant for its pro-tumorigenic properties. Given that both IL-8 and ETS1 expression correlate with the invasive phenotypes of cancer cells and angiogenesis , the study provides further evidence of the multifaceted promotion of breast cancer progression by SHP2, in this case via upregulation of the . . .

     

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