Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

HIGHLIGHTS

  • who: Proteogenomic integration reveals therapeutic and collaborators from the Department of Medicine, Washington University in StLouis, St. Louis, Missouri, USA. , McDonnell Genome Institute, Washington University in St. Louis have published the article: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 28/03/2017
  • what: The study demonstrates that MS-based proteomics can identify targets and highlights the potential of PDX drug response evaluation to annotate MS-based pathway activities. Of note, while iTRAQ and LFQ quantification were conducted separately and based on different features of the . . .

     

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