Proteolysis targeting chimeric molecules: tuning molecular strategies for a clinically sound listening

HIGHLIGHTS

• who: Federica Pedrucci et al. from the Department of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova have published the article: Proteolysis Targeting Chimeric Molecules: Tuning Molecular Strategies for a Clinically Sound Listening, in the Journal: (JOURNAL)
• what: In the last two decades, there has been a real flourishing of new molecular approaches aimed at improving the specificity, efficacy, safety, and pharmacokinetic profile of this class of compounds (Reviewed). The consistency of this model has been investigated in the bromodomain and extraterminal (BET) protein family involved in the epigenetic regulation of gene_expression through . . .
  

   

  

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