Proteome-wide landscape of solubility limits in a bacterial cell

HIGHLIGHTS

  • who: u00c1du00e1m Gyu00f6rkei from the Institut University of have published the research: Proteome-wide landscape of solubility limits in a bacterial cell, in the Journal: Scientific Reports Scientific Reports
  • what: The authors show that a substantial fraction (~ 35%) of the proteome remain soluble at concentrations much higher than those found naturally, indicating that many bacterial proteins are not expressed at levels close to their solubility limits. The work provides a global view of aggregation rates and hence solubility limits of proteins in a bacterial cell. The authors focused on monomeric proteins only (N=1631) to . . .

     

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