Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in aml

HIGHLIGHTS

• who: Sara J. C. Gosline from the Samples were collected and processed as described in detail previously [3]Briefly, all patients gave informed consent to participate in the Beat AML study, which had the approval and guidance of the Institutional Review Boards (IRB) from participating institutions. All samples used in this manuscript were collected at Oregon Health and Science University with a broad ‘research use' clause. Mononuclear cells (MNCs) were isolated from freshly obtained bone marrow or peripheral blood samples from AML patients via Ficoll gradient centrifugation. Isolated MNCs were utilized for genomic (, × WES have published the . . .
  

   

  

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