HIGHLIGHTS
- who: Meng-Hsuan Han from the DepartmentNorthwestern University have published the paper: Proteomics Analysis Reveals Overlapping Functions of Clustered Protocadherins*, in the Journal: (JOURNAL) of July/28,/2009
- what: The authors show that PCDH-␥s are present in large macromolecular complexes of ⬃1,000 kDa using both sucrose gradient (SG) ultracentrifugation and two-dimensional blue-native (2D BN)/SDS-PAGE methods. The analysis showed that 91 of 114 identified proteins (excluding PCDHs and hypothetical proteins) in PCDH-␥ complexes overlap with previously identified components in PSD preparations.
- future: Future analysis with the multidimensional protein . . .
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