Proteomics study of peripheral blood mononuclear cells in down syndrome children

HIGHLIGHTS

  • who: Chiara Lanzillotta and collaborators from the Department of Biochemical Sciences "ARossi Fanelli", Laboratory Affiliated to Istituto Pasteur, Sapienza University of Rome, Rome, Italy have published the paper: Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children, in the Journal: (JOURNAL)
  • what: The results of this study propose that PBMCs from DS children might be in an activated state where endoplasmic reticulum stress and increased production of radical species are one of the primary events contributing to multiple DS pathological features. The authors performed a high-definition label-free shotgun proteomics analysis on . . .

     

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