Protocol for a randomised, placebo-controlled, double-blinded clinical trial on the effect of oestrogen replacement on physical performance to muscle resistance exercise for older women with osteoarthritis of knee joint: the epok trial

HIGHLIGHTS

• who: Tomohiro Mitoma from the The EPOK trial is a two-arm exploratory double-blinded RCT with a, week intervention period, and the outcomes will be measured at baseline, months, and , monthsFigure , outlines the RCT phases. Eighty participants will be identified and randomly categorised into two groups: (1) MREP with transdermal oestrogen gel and (2) MREP with placebo gel. Eligibility will be assessed during screening. The Okayama University Hospital and Ochiai Hospital will conduct this trial. We have organised the EPOK trial team, including the Maniwa City Community General Support Center, which will assist with recruitment via . . .
  

   

  

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