Protofibrillar amyloid beta modulation of recombinant hcav2.2 (n-type) voltage-gated channels

HIGHLIGHTS

  • who: Eleni Kaisis et al. from the School of Pharmacy, University of Reading, Reading , UB, UK have published the research work: Protofibrillar Amyloid Beta Modulation of Recombinant hCaV2.2 (N-Type) Voltage-Gated Channels, in the Journal: Pharmaceuticals 2022, 15, x FOR PEER REVIEW of /2022/
  • what: In this short communication the authors show that recombinant hCav2.2/b1b /a2 d1 channels are modulated by human synthetic AD-related Ab1-42 peptides. This study shows that the recombinant human CaV 2.2/b1b /a2 d channel complex is a target for human synthetic protofibrillar Ab1 . . .

     

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