Proximity proteome mapping reveals pd-l1-dependent pathways disrupted by anti-pd-l1 antibody specifically in egfr-mutant lung cancer cells

HIGHLIGHTS

• who: Anudari Letian from the (UNIVERSITY) have published the research work: Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells, in the Journal: (JOURNAL)
• what: Because oncogenic KRAS and EGFR are the two most common mutations in NSCLC , the authors focused the studies on cell lines harboring either KRAS or EGFR mutations. To limit the analysis to most highly enriched EV proteins, the authors focused on proteins with EV to whole cell extract (WCE) ratio in the top quartile for each respective cell . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.