Pseudomonas aeruginosa transmigrates at epithelial cell-cell junctions exploiting sites of cell and senescent cell extrusion

HIGHLIGHTS

  • who: Guillaume Golovkine et al. from the University Grenoble Alpes, Grenoble, France, CNRS, ERL5261, Grenoble, France, CEA, iRTSV-BCI have published the paper: Pseudomonas aeruginosa Transmigrates at Epithelial Cell-Cell Junctions Exploiting Sites of Cell and Senescent Cell Extrusion, in the Journal: (JOURNAL) of August/17,/2015
  • what: Using real-time microscopy and a model epithelial barrier the authors show that P. aeruginosa employs a paracellular transmigration route taking advantage of altered cell-cell junctions at sites of cell division or when senescent cells are expelled from the cell layer. One of the major results . . .

     

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