Pseudorabies virus mutants lacking us9 are defective in cytoplasmic assembly and sorting of virus particles into axons and not in axonal transport

HIGHLIGHTS

  • who: Steven Adamou and colleagues from the Multiscale Microscopy Core, Oregon Health and Science University, Portland, OR, USA have published the article: Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport, in the Journal: Viruses 2023, 153 of /2023/
  • what: This process of anterograde axonal transport involves kinesin motors that move particles rapidly along microtubules. u03b1-herpesvirus anterograde transport has been extensively studied by characterizing the porcine (PRV) and HSV with most studies focused on two membrane proteins: gE/gI and US9 . . .

     

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