HIGHLIGHTS
- who: Psoralen mapping reveals a et al. from the Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA have published the paper: Psoralen mapping reveals a bacterial genome supercoiling landscape dominated by transcription, in the Journal: (JOURNAL) of September/07,/2021
- what: Using this method, the authors show that transcription from highly expressed ribosomal genes disrupts supercoiling over a 50 kb region--substantially farther than previously measured. This analysis showed that H-NS protein, which forms DNADNA bridges capable of constraining negative supercoils and restricting short-range interactions with surrounding DNA , is preferentially bound . . .
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