Ptk6 inhibits autophagy to promote uveal melanoma tumorigenesis by binding to socs3 and regulating mtor phosphorylation

HIGHLIGHTS

  • who: Bo Liu from the Xenografts assays Four- to six-week-old BALB/c nude mice were purchased from Charles River Laboratories, China, and housed in the specific-pathogen-free (SPF) laboratory animal room at Wenzhou Medical UniversityUveal melanoma cells (, u00d7, ) cultured in , u03bcL PBS were injected into the subcutaneous flank of the mice. The tumor size was measured every week with a caliper, and the tumor volume was calculated using the methods in the literature [32]. After , weeks, the excised tumors were weighed and photographed. have published the research work: PTK6 inhibits autophagy to promote uveal . . .

     

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