Ptpn1 deficiency modulates bmpr2 signaling and induces endothelial dysfunction in pulmonary arterial hypertension

HIGHLIGHTS

• who: Md Khadem Ali et al. from the Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, CA, USA have published the research work: PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension, in the Journal: Cells 2023, 316 of /2023/
• what: As endothelial dysfunction plays an important role in PH pathogenesis and as the BMPR2 receptor is highly expressed in endothelial cells, the authors aimed to investigate the role of PTPN1 in modulating BMPR2 signaling and its effect on PAEC function in PAH. The authors . . .
  

   

  

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