Purified, reconstituted cardiac ca2+-atpase is regulated by phospholamban but not by direct phosphorylation with ca2+/calmodulin-dependent protein kinase*

HIGHLIGHTS

• who: Laxma G. Reddy from the (UNIVERSITY) have published the article: Purified, Reconstituted Cardiac Ca2+-ATPase Is Regulated by Phospholamban but Not by Direct Phosphorylation with Ca2+/Calmodulin-dependent Protein Kinase*, in the Journal: (JOURNAL) of January/19,/1996
• what: The activity of the cardiac isoform was completely abolished if octyl glucoside was used for reconstitution and Triton X-100 gave about 2-fold better uptakes than C12E8.
• how: Taken together the results are consistent with the established effect of PLB on KCa but are inconsistent both with PLB forming an ion pore . . .
  

   

  

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