Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

HIGHLIGHTS

  • who: Mona Hoseini Soflaee from the University of Texas Southwestern Medical Center, Harry Hines Boulevard, Dallas, TX, USA have published the paper: Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The investigation provides a framework in which changes in cellular purine levels acutely alter the activity of central carbon metabolism to spur an adaptive morphological and migratory response.
  • how: The quantitative PCR data were analyzed with a Bio-Rad CFX Manager version 3.1.1517.0823.
  • future: Work is . . .

     

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