HIGHLIGHTS
- who: CD et al. from the University of Su00e3o Paulo, Brazil have published the research: Purinergic signaling: A gatekeeper of blood-brain barrier permeation, in the Journal: (JOURNAL)
- future: For validation purposes more in_vitro BBB models and in_vivo research targeting purinergic receptors on cells other than endothelial cells are required. of A2A receptor leads to progressive neurodegeneration and A2A antagonists have broad prospects for the treatment of CNS diseases. Since NECA is a broad-spectrum adenosine receptor agonist additional research is necessary to better comprehend the mechanisms by which A1/A2A/A2B receptors specifically mediate . . .
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