Purkinje cardiomyocytes of the adult ventricular conduction system are highly diploid but not uniquely regenerative

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  • who: Hirofumi Watanabe et al. from the Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, USA have published the article: Purkinje Cardiomyocytes of the Adult Ventricular Conduction System Are Highly Diploid but Not Uniquely Regenerative, in the Journal: (JOURNAL)
  • what: Using the conduction system expression marker Cntn2-GFP and the conduction system lineage marker Etv1CreERT2 the authors demonstrate that Purkinje CMs that comprise the adult ventricular conduction system are disproportionately diploid (33% vs. 4% of bulk ventricular CMs). Using EdU incorporation during the first postnatal week the authors demonstrate . . .

     

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