Pyrancoumarin derivative lp4c targeting of pyrimidine synthesis pathway inhibits mrsa lm and virulence

HIGHLIGHTS

• who: Staphylococcus aureus and collaborators from the University of Cambridge, United Kingdom have published the research work: Pyrancoumarin derivative LP4C targeting of pyrimidine synthesis pathway inhibits MRSA lm and virulence, in the Journal: (JOURNAL)
• what: The authors explored the mechanism of the pyrancoumarin derivative 2-amino-4-(2,6-dichlorophenyl)-3cyano-5-oxo-4H, 5H-pyrano chromene (LP4C), which Frontiers in Pharmacology
• how: The result showed that LP4C (100 and 200 u03bcg/ml) inhibited the formation of biofilm biomass of MRSA USA 300 significantly especially within 24 h . These results indicated that LP4C . . .
  

   

  

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