Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer

HIGHLIGHTS

• who: Reham M. M. El-Hazek from the National Center for British University have published the research work: Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer, in the Journal: Scientific Reports Scientific Reports of 19/Dec/2022
• what: This work describes the application of dual tail strategy for designing novel CA inhibitors.
• how: The authors carried out a docking validation for the docking protocol by pose retrieval experiment via docking the co-crystallized ligand and measuring RMSD between the docked and co-crystallized poses.
• future: Its . . .
  

   

  

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