Pyridazin-3(2h)-one as new fabp4 inhibitors suggested by molecular growing experiments “2279

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ACRONYMS

LAY DEFINITIONS

• fatty acid binding protein: Intracellular proteins that reversibly bind hydrophobic ligands including: saturated and unsaturated FATTY ACIDS; EICOSANOIDS; and RETINOIDS. They are considered a highly conserved and ubiquitously expressed family of proteins that may play a role in the metabolism of LIPIDS
• FABP4: aP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4)

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