Pyridinone derivatives as interesting formyl peptide receptor (fpr) agonists for the treatment of rheumatoid arthritis

HIGHLIGHTS

• who: Letizia Crocetti et al. from the NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff , have published the article: Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis, in the Journal: Molecules 2021, 26, 6583 acetamido and phenylpyridinone moieties of compound 14c are interchanged in space with respect to the of 22/09/2010
• what: The mixed FPR1/FPR2 agonist Cpd43 the agonist AT-01-KG and the pyridine derivative AMC3 have been shown to be effective in RA animal models. an extension of this research . . .
  

   

  

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