HIGHLIGHTS
- who: Yuhong Pan from the National Ilan University, Taiwan have published the research work: Pyroptosis in development, inflammation and disease, in the Journal: (JOURNAL)
- future: A more in-depth study on the role of GSDMB in pyroptosis and cancers are required.
SUMMARY
Compared with apoptosis, pyroptosis is a necroptotic and inflammatory programmed cell death mode mediated by inflammatory caspases. As previous studies have shown that caspase-1 can cleave the pro-inflammatory cytokines pro-IL-1b and pro-IL-18, the term pyroptosis was therefore coined in 2001 to indicate inflammatory . . .
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