Pyruvate supports ret-dependent mitochondrial ros production to control mycobacterium avium infection in human primary macrophages

HIGHLIGHTS

• who: Lisa Marie Rø and colleagues from the Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Kyushu University, Japan have published the research: Pyruvate Supports RET-Dependent Mitochondrial ROS Production to Control Mycobacterium avium Infection in Human Primary Macrophages, in the Journal: (JOURNAL)
• what: The authors report that macrophages rely on glycolysis and RET to control M. avium infection and provide molecular evidence linking pyruvate, the end-product of glycolysis, to anti-mycobacterial mtROS production. response. The authors show evidence that the killing mechanism acts through the . . .
  

   

  

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