Qingluo tongbi formula alleviates hepatotoxicity induced by tripterygium wilfordii hook. f. by regulating excessive mitophagy through the perk-atf4 pathway

HIGHLIGHTS

  • who: Tripterygium wilfordii hook. f. and collaborators from the The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China, Jiangsu Provincial Key Laboratory of have published the research: Qingluo Tongbi Formula Alleviates Hepatotoxicity Induced by Tripterygium wilfordii Hook. F. by Regulating Excessive Mitophagy Through the PERK-ATF4 Pathway, in the Journal: (JOURNAL)
  • what: The study proved that in mice treated with TW, the expression of mitophagy-related proteins was abnormal, which was characterized by the increased expression level of DRP1, while the expression levels of MFN1 and FIS1 did not change significantly.
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