Qpcr detection of mycobacterium leprae dna in urine samples of leprosy patients using the rlep gene target

HIGHLIGHTS

  • What: The aim of this work was to evaluate the sensitivity and specificity of qPCR and conventional PCR for the detection of M. leprae in urine samples among new untreated patients, in patients on MDT, and in patients who have been released from treatment. This study demonstrated that M. leprae DNA could be quantified in different clinical samples, such as slit skin smears, blood, and urine samples, using the Rlep gene target and qPCR across different clinical forms of leprosy among different study groups, including new untreated, MDT, and RFT.
  • Who: Mycobacterium leprae et al . . .

     

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