Quality control and quantification in ig/tr next-generation sequencing marker identification: protocols and bioinformatic functionalities by euroclonality-ngs

HIGHLIGHTS

  • who: Henrik Knecht from the (UNIVERSITY) have published the article: Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS, in the Journal: (JOURNAL)
  • what: The authors show its successful application and robustness for clinical laboratories that want to implement the EuroClonality-NGS assays for marker identification and quantification. The experiments show that the cPT-QC is a valuable tool to monitor reproducibility of results and to identify primer perturbations and other deviations in the wet-lab protocol, as they introduce detectable changes to the sequencing . . .

     

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