Quantification of localized nad+ changes reveals unique specificity of nad+ regulation in the hypothalamus

HIGHLIGHTS

  • who: Sean Johnson from the Animal studies C BL/ J male mice were purchased from Charles River Japan or Jackson LaboratoryMice were maintained ad libitum on a regular chow diet on a , h light/dark cycle. All animal studies were reviewed and approved by the Institutional Animal Ethics Committees at RIKEN-BDR and the Institute of Biomedical Research and Innovation in the FBRI, Kobe, Japan (Figs., ) or by the Institutional Animal Care and Use Committee of Washington University in St. Louis, Missouri, USA (Protocol No., ) (Fig., ). NAD+ measurement by HPLC NAD+ levels were determined using an HPLC . . .

     

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