Quantification of protein glycosylation using nanopores

HIGHLIGHTS

• who: Roderick Corstiaan Abraham Versloot and colleagues from the (UNIVERSITY) have published the Article: Quantification of Protein Glycosylation Using Nanopores, in the Journal: (JOURNAL) of June/29,/2022
• what: The authors show that hydrophilic or glycosylated peptides translocate too quickly across FraC nanopores to be recognized. This work shows that nanopores can be used similarly to mass spectrometry for the detection and quantification of PTMs in proteins. The authors show that a nanopore with an aromatic constriction together with high electrolyte concentrations and a low pH increases the dwell time for the translocation of hydrophilic . . .
  

   

  

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